Cardiac reperfusion damage prevented by a nitroxide free radical.
نویسندگان
چکیده
منابع مشابه
Assessing free radical damage.
Background: Three types of cell lines have been established from mouse blastocysts: embryonic stem (ES) cells, trophoblast stem (TS) cells, and extra-embryonic endoderm (XEN) cells, which have the potential to differentiate into their respective cognate lineages. ES cells can differentiate in vitro not only into somatic cell lineages but into extra-embryonic lineages, including trophectoderm an...
متن کاملMyocardial ischemia, reperfusion and free radical injury.
Reperfusion of coronary arteries to limit myocardial ischemic injury and extent of myocardial necrosis is possible by either the use of fibrinolytic therapy, coronary angioplasty or coronary artery bypass surgery. The concept that early reperfusion may salvage jeopardized myocardium is derived from basic experimental studies which purported to demonstrate that the ultimate extent of irreversibl...
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TEMPOL, a cyclic nitroxide stable radical blocks biological damage by breaking chain reactions through termination reaction with free radicals, and by inhibiting the catalytic effect of transition metals. This study tested its protective effect on two models of experimental colitis as free radicals play an important part in their pathogenesis. TEMPOL was given intragastrically immediately after...
متن کاملPreventing oxygen free radical damage by proanthocyanidin in obstructive jaundice.
OBJECTIVE Tissue damage and endotoxemia in obstructive jaundice are attributed to the increase in oxygen free-radicals. We aimed at evaluating the possible protective effect of grape seed proanthocyanidin extract (GSPE), which is a potent exogenous free-radical scavenger and antioxidant. MATERIAL AND METHODS The study was performed at the Necmettin Erbakan University Meram School of Medicine ...
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Muhammed Aydin, Mehmet Atilla Tasdelen, Tamer Uyar, Steffen Jockusch, Nicholas J. Turro,4,z Yusuf Yagci Department of Chemistry, Faculty of Science and Letters, Istanbul Technical University, Maslak, TR-34469 Istanbul, Turkey Department of Polymer Engineering, Faculty of Engineering, Yalova University, TR-77100 Yalova, Turkey UNAM-Institute of Materials Science and Nanotechnology, Bilkent Unive...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1991
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.88.11.4680